Management of Bleeding Complications after IV Alteplase

Today’s pearl describes potential treatment options for patients that develop an intracranial hemorrhage following the administration of IV alteplase (tPA).

A difficult situation with no great options.
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Blood Pressure Management in ICH: ATACH-2 Trial with a Focus on the Meds

Does intensive blood pressure control improve outcomes and reduce hematoma expansion in acute intracerebral hemorrhage (ICH)? The INTERACT-2 trial previously compared intensive vs. conservative blood pressure control in ICH patients and found no difference in death or disability between the two groups. Enter the ATACH-2 trial, published in the New England Journal of Medicine September 15, 2016. Dr. Ryan Radecki provides his review of the article on his EM Lit of Note site.

The purpose of this post is to evaluate the antihypertensive regimens used. Were they appropriate and are they applicable to practice everywhere?
Continue reading “Blood Pressure Management in ICH: ATACH-2 Trial with a Focus on the Meds”