Sulfamethoxazole/Trimethoprim Drug Interactions Important for EM Clinicians

Today’s pearl highlights two interactions that are important for Emergency Medicine clinicians to know.

What are the risks? How common are they?
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Antibiotic Effects on Oral Contraceptives

Today’s pearl addresses a misconception regarding a drug interaction between oral contraceptives and antibiotics.

Are back-up methods of contraception required? Does this apply to all antibiotics?
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Beta-Agonist Alternatives to Nebulized Albuterol for Treatment of Hyperkalemia

Today’s pearl provides some alternative methods to treat patients with hyperkalemia if nebulized albuterol is not an option.

What route? Which medication? How much?
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Magnesium for Atrial Fibrillation Rate Control in the ED

Today’s pearl is a continuation of Pearl 42: Medication Pearls for Atrial Fibrillation Management in the ED and reviews the role of magnesium for the treatment of atrial fibrillation.

Does magnesium reduce HR? How much and how fast to administer?
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Medication Pearls for Atrial Fibrillation Management in the ED

Today’s pearl highlights 5 main points related to the treatment of atrial fibrillation.

Should you give a beta blocker or a calcium channel blocker? What dose should you use?
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Use of IV Iodinated Contrast Media in Patients with Preexisting Renal Disease

Today’s pearl reviews some of the literature and recommendations regarding the use of iodinated contrast in patients with kidney disease

Will it cause an acute-on-chronic injury? Is it safe?
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Importance of Boluses with Rate Changes for Opioid & Benzodiazepine Infusions

Today’s pearl provides some advice on how to properly increase sedative rates for intubated patients

Why do boluses matter?
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