QTc Prolongation and Torsades de Pointes with Droperidol in the Emergency Department

How common is QTc prolongation or Torsades de Pointes (TdP) in ED patients getting droperidol?

Actually quite rare!

In 30,000 patients, TdP occurred once (the patient had multiple risk factors and TdP didn’t reoccur when re-challenged).

Prior data covered in 2015 @aaeminfo position statement.

Author: Bryan D. Hayes, PharmD

Attending Pharmacist, Emergency Medicine and Toxicology, Massachusetts General Hospital; Assistant Professor of EM, Harvard Medical School

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