Management of Bleeding Complications after IV Alteplase

Today’s pearl describes potential treatment options for patients that develop an intracranial hemorrhage following the administration of IV alteplase (tPA).

A difficult situation with no great options.
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Management of Opioid Use Disorder in the Emergency Department


Over the past year, a group of physicians and pharmacists with expertise in emergency medicine, toxicology, and addiction medicine developed a white paper for the American Academy of Emergency Medicine (AAEM) on Management of Opioid Use Disorder in the Emergency Department. It is our attempt to share current best practices and provide comprehensive evidence-based recommendations for providers in acute care settings managing patients being harmed-or at risk to be harmed-by opioids.

The guideline is set up as 48 discrete, commonly-encountered questions with extensively-referenced, high-yield answers answer based on available evidence and expert consensus within our group.

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The New Community-Acquired Pneumonia Guidelines are Finally Here!

Today’s pearl is a brief overview the Infectious Diseases Society of America (IDSA) and American Thoracic Society (ATS) update to the Adult Community-Acquired Pneumonia (CAP) guidelines, with a focus on medications.

After 12 long years, the highly anticipated update to the CAP guidelines has arrived!
Continue reading “The New Community-Acquired Pneumonia Guidelines are Finally Here!”