Pearls – Page 3 – The PharmERToxGuy

ECMO for Poisoned Patients

Today’s pearl is about treating patient in refractory toxin-induced cardiogenic shock with venoarterial-extracorporeal membrane oxygenation (VA-ECMO).

Is ECMO an effective treatment?

Blood Cultures Before Antibiotics Matter

Today’s pearl is why it is important to obtain blood cultures prior to antibiotic administration whenever possible.

The difference a few minutes can make.

Black Box Drugs We Use – Fluoroquinolones

Today’s pearl is why I think fluoroquinolones should be relegated to second or third-line therapy for most infections.

And should be renamed “fluoroquino-leave-them-alones”

Management of Opioid Use Disorder in the Emergency Department

Introduction

Over the past year, a group of physicians and pharmacists with expertise in emergency medicine, toxicology, and addiction medicine developed a white paper for the American Academy of Emergency Medicine (AAEM) on Management of Opioid Use Disorder in the Emergency Department. It is our attempt to share current best practices and provide comprehensive evidence-based recommendations for providers in acute care settings managing patients being harmed-or at risk to be harmed-by opioids.

The guideline is set up as 48 discrete, commonly-encountered questions with extensively-referenced, high-yield answers answer based on available evidence and expert consensus within our group.

Continue reading “Management of Opioid Use Disorder in the Emergency Department”

The New Community-Acquired Pneumonia Guidelines are Finally Here!

Today’s pearl is a brief overview the Infectious Diseases Society of America (IDSA) and American Thoracic Society (ATS) update to the Adult Community-Acquired Pneumonia (CAP) guidelines, with a focus on medications.

After 12 long years, the highly anticipated update to the CAP guidelines has arrived!

Toxicology Pearls from the 2019 North American Congress of Clinical Toxicology

Today’s pearls are some of the high points from the recent NACCT conference tweeted out by Mike O’Brien @MikeEMPharmD

Timely toxicology tweets and treatment tips

Capsaicin for Cannabinoid Hyperemesis Syndrome

Today’s pearl is a nontraditional treatment for nausea/vomiting in patients with Cannabinoid Hyperemesis Syndrome.

An easy and topical option for patients with symptoms refractory to normal therapies

Duration of CPR After tPA in a Cardiac Arrest secondary to PE – Update

Today’s pearl is an update about the amount of time to continue a code following the administration of alteplase.

Are the European guidelines in line with current practice?

The ‘Ceiling’ Effect of NSAIDs

Today’s pearl is about the dose ceiling effect of NSAIDs (the idea that increasing doses does not lead to further pain relief)

Are we giving to much without benefit?

More isn’t always better.

Timing of Basal Insulin Administration in Patients with DKA

Today’s pearl is about the potential benefits of administering basal subcutaneous insulin early for patients with diabetic ketoacidosis (DKA) requiring an insulin infusion

Is earlier better?